The Dynamic of Heterosexual Transmission of HIV-AIDS Model with Treatment

Authors

  • K. A. Bashiru Department of Mathematical Sciences, Osun State University
  • T. A. Ojurongbe Department of Mathematical Sciences, Osun State University
  • M. Lawal Department of Mathematical and Computer Sciences, Fountain University, Osogbo, Nigeria

DOI:

https://doi.org/10.53704/fujnas.v6i2.150

Abstract

A Mathematical Model of HIV/AIDS with Heterosexual transmission in the presence of treatment was examine in this paper, it ascertained the impact of treated individuals on the transmission dynamics of HIV/AIDS. Equilibrium points of the model system were found, stability analysis and numerical simulation were carried out, it was discovered that HIV/AIDS can die out with test of time as Ro < 1 . It was observed that the model had a disease free equilibrium which was asymptotically stable for Ro < 1 and unstable for Ro > 1. Graphical representations of the numerical analysis showing the effect of treatment on the model were also presented.

Keywords: HIV/AIDS, Heterosexual Transmission, ARVs, Compartmental model, Disease Free and Endemic equilibrium, Treatment, and Basic Reproductive Number

References

Bashiru K.A (2005): Stochastic modeling of specific modes of transmission of HIV/AIDS epidemic with reference to Nigeria. M.Tech. Thesis, Federal University of Technology, Akure, Ondo State.

Bashiru, K.A and O.A Fasoranbaku O.A (2009): Statistical Modelling of Mother – to – Child and Heterosexual Modes of Transmission ofHIV/AIDS Epidemic” The Pacific Journal of Science and Technology, vol. 10. No. 2.

Bashiru K.A (2014): Stochastic and Dynamic Analysis of HIV/AIDS Epidemy in Nigeria. (Phd Thesis): Federal University of Technology Akure, Nigeria.

Derrick N.R and Grossman S.L (1976): Differential Equation with Applications, Addison Wesley Publishing Company, Inc. Phillipines.

Epstein H (2009). Universal voluntary HIV testing and immediate antiretroviral therapy. Lancet,373:1078-1079; author reply 1080-1071.

Gortmaker S.L, Hughes M, Cervia J, Brady M, Johnson G.M , Seage G.R, Song Lin Ye, Dankner W.M and Oleske (2001) : “ Effects of combination therapy including protease inhibitors on mortality among children and adolescents infected with HIV-1”, The New England J. of Med., (345) 21,pp. 1522 – 1528.

Naresh R., Tripathi A., Omar S.,(2006),“Modelling the spread of AIDS epidemic with vertical transmission”. Applied Mathematics and Computation Vol. 178, pp 262-272.

Olowofeso O.E and Waema R.(2005): Mathematical Modelling for Human Immunodeficiency Virus (HIV) Transmission using Generating Function Approach. Kragujevae j. Sci., Vol. 27: 115 – 130.

Shaffer N, Chuachoowong R, Monk P.H, Bhadrakon C, Siriwasin W, Young N.L, Chotpitayasunondh T, Chearskul S, Roongpisuthipong A, Chinayon P, Karon J, Mastro T, Simons R.J (1999): “Short – course of zidovudine for perinatal HIV- 1 transmission in Bangkok, Thailand: A randomized controlled trial” , The Lancet (353), pp. 773 – 780.

Yanan Zhao and Daqing Jiang (2013): The extinction and persistence of the stochastic SIS epidemic model with vaccination. Statistical mechanics and its application, volume 392, issue 20 Pp4916 – 4927.

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Published

2017-12-29

How to Cite

The Dynamic of Heterosexual Transmission of HIV-AIDS Model with Treatment. (2017). Fountain Journal of Natural and Applied Sciences, 6(2). https://doi.org/10.53704/fujnas.v6i2.150